Symbol
Name
ID

Taf4b
TATA-box binding protein associated factor 4b
MGI:2152345

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Elevated circulating follicle stimulating hormone level	Abnormal circulating luteinizing hormone concentration	Abnormal circulating testosterone concentration	Abnormal prolactin level
Disease(s) Associated with TAF4B
spermatogenic failure 13

Mouse Phenotypes

increased granulosa cell apoptosis

decreased granulosa cell proliferation

absent mature ovarian follicles

decreased primordial ovarian follicle number

decreased secondary ovarian follicle number

abnormal tertiary ovarian follicle number

decreased tertiary ovarian follicle number

absent ovarian follicles

increased atretic ovarian follicle number

impaired ovarian folliculogenesis

small ovary

ovary cyst

ovary degeneration

seminiferous tubule degeneration

increased Leydig cell number

decreased testis weight

small testis

premature ovarian failure

Availability

Mouse Genotype

Taf4b^tm1Rtj/Taf4b^tm1Rtj

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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